Teams: Vandenberghe Lab
Sumant Brahmankar
Research Lab Tech II
Education Background: M.S Chemical Engineering, Arizona State University.
B.S Chemical Engineering, MIT-WPU Pune
Research Projects: AAV Production and NGS Library Preparation
Research Interest: AAV and CRISPR-Cas9 associated Gene Therapy
Career Ambition: Gene Therapy Scientist
Awards and Honors: Engineering Graduate Fellowship, The Master’s Opportunity for Research in Engineering
sbrahmankar@meei.harvard.edu
- Vandenberghe Lab > Hui-Chen Cheng, MD PhD
Hui-Chen Cheng, MD PhD
Visiting Research Scholar
Education Background:
- M.D., National Yang-Ming University, Taipei, Taiwan
- Ph.D., Program in Molecular Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
Research Interest: Gene Therapy, Inherited Neurodegenerative Diseases, Inherited Optic Neuropathy and Retinopathy
Career Ambition: Apply gene therapy to optic neuropathy and retinopathy in various conditions
Memberships:
- Asia Pacific Academy of Ophthalmology
- Ophthalmologic Society of Taiwan
hcheng11@meei.harvard.edu
Vandenberghe Lab Team
Luk H. Vandenberghe, PhD
Director
Nerea Zabaleta, PhD
Investigator
Anil Chekuri, PhD
Investigator
Reynette Estelien
Lead Research Lab Tech
Jiten Doshi, PhD
Postdoctoral Research Fellow
Huachun Liu, PhD
Postdoctoral Research Fellow
Paige Osborn
Program Coordinator
Matt Chagnon
Research Lab Tech I
Yu Ning, PhD
Postdoctoral Research Fellow
Sumant Brahmankar
Research Lab Tech II
- Vandenberghe Lab > Yu Ning, PhD
Yu Ning, PhD
Postdoctoral Research Fellow
Education Background: BS in Biotechnology; PhD in Biology, Texas Tech University
Research Projects: Identify modulators that can alter the capability of a cell to produce AAV vectors.
Research Interest: AAV manufacturing, Gene therapy.
Career Ambition: Advancing medicine through genomic technologies for the benefit of individuals and society.
yning3@meei.harvard.edu
Vandenberghe Lab Team
Luk H. Vandenberghe, PhD
Director
Nerea Zabaleta, PhD
Investigator
Anil Chekuri, PhD
Investigator
Reynette Estelien
Lead Research Lab Tech
Jiten Doshi, PhD
Postdoctoral Research Fellow
Huachun Liu, PhD
Postdoctoral Research Fellow
Paige Osborn
Program Coordinator
Matt Chagnon
Research Lab Tech I
Hui-Chen Cheng, MD PhD
Visiting Research Scholar
Sumant Brahmankar
Research Lab Tech II
Matt Chagnon
Research Lab Tech I
Education: Bachelor’s in Health Sciences, Minors in Psychology and Chemistry
Research Interest: Stem Cell Therapy, Neurodegenerative Diseases
Career Ambition: Lab Coordinator
Awards & Honors: Dean’s List (all years of college)
mchagnon2@meei.harvard.edu
- Vandenberghe Lab > Paige Osborn
Paige Osborn
Program Coordinator
Education Background: B.S. Health Science Studies from Quinnipiac University
Career Ambition: Continue to explore and pursue opportunities in Healthcare Administration
posborn@meei.harvard.edu
Vandenberghe Lab Team
Luk H. Vandenberghe, PhD
Director
Nerea Zabaleta, PhD
Investigator
Anil Chekuri, PhD
Investigator
Reynette Estelien
Lead Research Lab Tech
Jiten Doshi, PhD
Postdoctoral Research Fellow
Huachun Liu, PhD
Postdoctoral Research Fellow
Matt Chagnon
Research Lab Tech I
Yu Ning, PhD
Postdoctoral Research Fellow
Hui-Chen Cheng, MD PhD
Visiting Research Scholar
Sumant Brahmankar
Research Lab Tech II
- Vandenberghe Lab > Huachun Liu, PhD
Huachun Liu, PhD
Postdoctoral Research Fellow
Education Background: BS in Agronomy, Zhejiang University, China; PhD in Molecular Biology, UCLA
Research Projects: Capsid engineering of AAV
Research Interest: Delivery method for gene therapy
Career Ambition: Develop translational products to benefit patients
hliu41@meei.harvard.edu
Vandenberghe Lab Team
Luk H. Vandenberghe, PhD
Director
Nerea Zabaleta, PhD
Investigator
Anil Chekuri, PhD
Investigator
Reynette Estelien
Lead Research Lab Tech
Jiten Doshi, PhD
Postdoctoral Research Fellow
Paige Osborn
Program Coordinator
Matt Chagnon
Research Lab Tech I
Yu Ning, PhD
Postdoctoral Research Fellow
Hui-Chen Cheng, MD PhD
Visiting Research Scholar
Sumant Brahmankar
Research Lab Tech II
- Vandenberghe Lab > Jiten Doshi, PhD
Jiten Doshi, PhD
Postdoctoral Research Fellow
Education: Bachelors and Masters in Biotechnology, Doctoral degree in Synthetic Biology
Research Projects: I am undertaking the existing challenge associated with the manufacturing of AAV vectors by adopting a synthetic biology approach in engineering the key molecular determinants.
Research Interest: Gene Therapy, Synthetic Biology, DNA/RNA therapeutics, Viral vectors development/engineering
Career Ambition: Development of genetic medicines while using the principles of synthetic biology
Awards & Honors: Scholarships for both Masters and Bachelors studies from the respective educational institutions.
jdoshi1@meei.harvard.edu
Vandenberghe Lab Team
Luk H. Vandenberghe, PhD
Director
Nerea Zabaleta, PhD
Investigator
Anil Chekuri, PhD
Investigator
Reynette Estelien
Lead Research Lab Tech
Huachun Liu, PhD
Postdoctoral Research Fellow
Paige Osborn
Program Coordinator
Matt Chagnon
Research Lab Tech I
Yu Ning, PhD
Postdoctoral Research Fellow
Hui-Chen Cheng, MD PhD
Visiting Research Scholar
Sumant Brahmankar
Research Lab Tech II
- Vandenberghe Lab > Reynette Estelien
Reynette Estelien
Lead Research Lab Tech
Education: BS in Biological Sciences/Biotech, University of Massachusetts Lowell, RALAT Certified, Certificate in Biomedical Laboratory Sciences, Boston University
Research Project: Gene Therapy
Research Interest: Gene therapy and drug discovery
Career Ambition: To further my study in Animal Research and Epidemiology
Membership: Member of New England Branch for American Association of Laboratory Animal Sciences (NEBAALAS)
reynette_estelien@meei.harvard.edu
Vandenberghe Lab Team
Luk H. Vandenberghe, PhD
Director
Nerea Zabaleta, PhD
Investigator
Anil Chekuri, PhD
Investigator
Jiten Doshi, PhD
Postdoctoral Research Fellow
Huachun Liu, PhD
Postdoctoral Research Fellow
Paige Osborn
Program Coordinator
Matt Chagnon
Research Lab Tech I
Yu Ning, PhD
Postdoctoral Research Fellow
Hui-Chen Cheng, MD PhD
Visiting Research Scholar
Sumant Brahmankar
Research Lab Tech II
- Vandenberghe Lab > Anil Chekuri, PhD
Anil Chekuri, PhD
Investigator
Anil Chekuri, PhD, has been focused on understanding the molecular bases of Inherited Retinal Degenerations (IRDs) and Age-related Macular Degeneration (AMD). He aims to investigate key molecular pathways underlying several forms of retinal dystrophies and development of therapeutic targets to rescue retinal function. His research also focuses on the development of novel Adeno Associated Viral (AAV) vectors with improved retinal tropism and efficacy for therapeutic delivery suitable for translational studies. Dr. Chekuri is currently working to develop gene therapy for various forms of retinal disorders.
achekuri@mgh.harvard.edu
Vandenberghe Lab Team
Luk H. Vandenberghe, PhD
Director
Nerea Zabaleta, PhD
Investigator
Reynette Estelien
Lead Research Lab Tech
Jiten Doshi, PhD
Postdoctoral Research Fellow
Huachun Liu, PhD
Postdoctoral Research Fellow
Paige Osborn
Program Coordinator
Matt Chagnon
Research Lab Tech I
Yu Ning, PhD
Postdoctoral Research Fellow
Hui-Chen Cheng, MD PhD
Visiting Research Scholar
Sumant Brahmankar
Research Lab Tech II
Nerea Zabaleta, PhD
Investigator
Nerea Zabaleta, PhD, is an Instructor at Harvard Medical School. Her research lab forms part of the Grousbeck Gene Therapy Center at Massachusetts Eye and Ear Infirmary in Boston, USA, and of the Ocular Genomics Institute. She received a PhD degree in biomedical research from the University of Navarra, Spain, in 2018. She has a strong background in translational gene editing and gene therapy for inherited liver metabolic disorders as well as preclinical development of vaccines. Her laboratory aims at developing and optimizing adeno-associated viral vector (AAV)-based therapies for inherited and infectious disorders. Her goal is to create custom AAV vectors that adequate to the needs of each disease and target specific cell types rather than specific organs, creating more effective and safer therapies. Her work has been published in high impact journals, and she is inventor of two patents, including an AAV-based vaccine platform. Additionally, she is a board member of ECUSA (Spanish Scientist in the USA, non-profit) and volunteers her time to advocating for inclusion and gender equity.
nerea_zabaletalasarte@meei.harvard.edu