Luk H. Vandenberghe, PhD

Director (on leave)

Luk H. Vandenberghe, PhD, is an Associate Professor at Harvard Medical School and Associate Member of the Broad Institute of Harvard and MIT in Boston, MA, USA. He directs the Grousbeck Gene Therapy Center at Massachusetts Eye and Ear Infirmary in Boston, USA, a part of the the Ocular Genomics Institute, a bench to bedside research program to study, diagnose, and develop treatments for diseases of the eye.

He received a degree in cellular and genetic engineering from the University of Leuven, Belgium. His previous work led to the discovery of novel AAV serotypes such as AAV9, novel insights into AAV structure-function, and vector immunobiology. His laboratory aims to gain a deeper understanding of mechanisms of gene transfer, to develop technologies to overcome hurdles to gene therapy clinical applications, and to translate specific gene therapy programs in vision, hearing, and other fields. Recent studies leverage structural and evolutionary information on AAV as a starting point for the rational design of synthetic viral vector systems, a first generation of which is referred to as AncAAVs which are now progressing to the clinic for a number of indications. Dr. Vandenberghe previously co-founded GenSight Biologics and Akouos. He also is a founder, board member, and advisor to Odylia Therapeutics, a non-profit catalyzing translation for gene therapies within the challenging field of ultra-rare disorders. Dr. Vandenberghe has over 50 peer reviewed publication and more than a dozen licensed patents, mostly related to gene therapy methods, technologies, and applications.

luk.vandenberghe@gmail.com

Vandenberghe Lab Team

  • Nerea Zabaleta, PhD

    Investigator

  • Anil Chekuri, PhD

    Investigator

  • Jackson W. Lau, MHA

    Senior Lab Manager

  • Urja Bhatt, MS

    Lead Research Lab Tech

  • Julio Sanmiguel

    Lead Research Lab Tech

  • Reynette Estelien

    Lead Research Lab Tech

  • Michael Florea

    PhD Candidate

  • Jiten Doshi, PhD

    Postdoctoral Research Fellow

  • Huachun Liu, PhD

    Postdoctoral Research Fellow

  • Aruna Kumar Chelluboyina, PhD

    Postdoctoral Research Fellow

  • Paige Osborn

    Program Coordinator

  • Max Miller

    Research Lab Tech I

© 2018 Grousbeck Gene Therapy Center

20 Staniford Street, Boston, MA 02114